Which is responsible for the transmission

Immune cells and enhance their effect on the tumor. Also, for treatment, immune T-lymphocytes that have already been in contact with. The neoplasm canand modifi in the laboratory and inject again in larger quantities or with improv properties. The concept of cancer vaccines is generally bas on the fact that malignant cells have specific antigens. And the immune system can be “train” to find these antigens in order to fight the tumor. However, vaccines for the treatment of malignant diseases have not yet cop with their task. Firstly, the antigens that produce cancer cells are also found in. Other healthy ones, so the immune system can “ignore” the tumor, and secondly.

Be taken from the patient grown

The neoplasms themselves are protect from immune Sweden Phone Numbers List cells, blocking their function and preventing penetration into the tumor. Vaccines so far stimulate the immune response to the tumor too weakly to have a significant effect on the condition of patients and ruce mortality. KRAS gene inhibitor drugs The proto-oncogene KRAS, of signals during the functioning of cells, mutates especially often. Its mutation can trigger tumor growth and the development of cancer of the lungs, pancreas, intestines and other organs. Mutat KRAS is found in % of patients with lung cancer, % with pancreatic cancer, and % with colon cancer.

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Sotorasib becamethe first approv drug

The search for drugs that inhibit  turn off” – the USA CFO damag gene has become a promising area in oncology. One such substance, sotorasib, has already been register with the FDA (US Food and Drug Administration).  that directly targets the damag KRAS gene. Clinical studies have shown relatively low toxicity and good short-term results. One of the promising drugs, according to a publication in the journal Nature, is LY – while it is at the research stage , but has already shown times higher efficacy than sotorasib.

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